Approximately 1-2% of total body magnesium is located in the extracellular fluid space. Trade Name: Epsom Salt, Magnesium Sulfate, U.S.P. Cyclosporine If not breathing, give artificial respiration. DOT Classification: CLASS 4.1: Flammable solid. Been elevating foot when possible. Heart block also may occur at this or lower serum levels of magnesium. Intravenous magnesium should not be given to mothers with toxemia of pregnancy during the two hours preceding delivery. In severe pre-eclampsia or eclampsia, the total initial dose is 10 to 14 g of Magnesium Sulfate. Magnesium Sulfate should be used during pregnancy only if clearly needed. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. When used judiciously it effectively prevents and controls the convulsions of eclampsia without producing deleterious depression of the central nervous system of the mother or infant. Special protective equipment and precautions for firefighters Wear self-contained, approved breathing apparatus and full protective clothing, including eye protection and boots. Following intramuscular administration the onset of action occurs in about one hour and persists for three to four hours. Use a mercury free magnesium sulfate cream ( Kirkman's Labs) sells this. Prevent contact with skin and eyes. WARNING: DO NOT USE FLEXIBLE CONTAINER IN SERIES CONNECTIONS. Magnesium plays many crucial roles in the body, such as supporting muscle and nerve function and energy production. Skin Protection If solution contact with unprotected skin is likely, use of impervious gloves is a prudent practice. Magnesium is excreted solely by the kidney. Potassium Magnesia Sulfate Note: Blank spaces are not permitted. These include flushing, sweating, hypotension, depressed reflexes, flaccid paralysis, hypothermia, circulatory collapse, cardiac and central nervous system depression proceeding to respiratory paralysis. Magnesium is excreted solely by the kidney at a rate proportional to the serum concentration and glomerular filtration. If you have any questions, ask your doctor or pharmacist.. 3 Product Name: Magnesium Sulfate Injection, USP Respiratory Protection Respiratory protection is not needed during normal product use. Magnesium is excreted solely by the kidney. May contain sulfuric acid and/or sodium hydroxide for pH adjustment. Section I Manufacturer’s name North Country Organics Emergency Telephone Number 802-222-4277 The administration of Magnesium Sulfate in Water for Injection outside of its approved indication in pregnant women should be by trained obstetrical personnel in a hospital setting with appropriate obstetrical care facilities. Relevant identified uses of the substance or mixture and uses advised against Use of the substance/mixture : Laboratory chemicals 1.3. There are retrospective epidemiological studies and case reports documenting fetal abnormalities such as hypocalcemia, skeletal demineralizations, osteopenia and other skeletal abnormalities with continuous maternal administration of Magnesium Sulfate for more than 5-7 days.1-12 Magnesium Sulfate in Water for Injection should be used during pregnancy only if clearly needed. Belongs to the Following Reactive Group (s) Metals, Elemental and Powder, Active The pH is 4.5 (3.5 to 6.5). To report SUSPECTED ADVERSE REACTIONS, contact Mylan at 1-877-446-3679 (1-877-4-INFO-RX) or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. Serum magnesium levels usually sufficient to control convulsions range from 3 to 6 mg/100 mL (2.5 to 5 mEq/liter). Magnesium Sulfate in Water for Injection is a sterile, nonpyrogenic, clear, colorless solution of Magnesium Sulfate heptahydrate in water for injection. Epsom salts is magnesium sulfate or magnesium sulfate heptahydrate, also known as sulfur bitter, bitter... What else can I do help heal my mild to moderate sprained ankle ? Magnesium Sulfate, USP heptahydrate is chemically designated MgSO4 • 7H2O, colorless crystals or white powder freely soluble in water. If swallowed DO NOT induce vomiting. (See OVERDOSAGE.). Discard unused portion. Manufactured by: However, chronically low levels can increase the risk of high blood pressure, heart disease, type 2 diabetes and osteoporosis. Contact may cause irritation to eye, skin, and respiratory system. Magnesium (Mg++) is an important cofactor for enzymatic reactions and plays an important role in neurochemical transmission and muscular excitability. sulfur oxides). Subcutaneous physostigmine, 0.5 to 1 mg may be helpful. Magnesium Sulfate in Water for Injection is indicated for the prevention and control of seizures in preeclampsia and eclampsia, respectively. Immediate medical attention and special treatment, if necessary No additional information available … Because magnesium is removed from the body solely by the kidneys, the drug should be used with caution in patients with renal impairment. Normal serum magnesium levels range from 1.3 to 2.1 mEq/liter. Manufactured for: Magnesium is highly flammable, especially when powdered or shaved into thin strips, though it is difficult to ignite in mass or bulk. Flammable limits: This material is noncombustible. Epsom Salts contain mercury. In the presence of severe renal insufficiency, frequent serum magnesium concentrations must be obtained and the maximum dosage of Magnesium Sulfate is 20 g per 48 hours. Information about your device and internet connection, including your IP address, Browsing and search activity while using Verizon Media websites and apps. Powdered magnesium reacts violently with performic acid [Berichte 48:1139. Magnesium exposed to moist fluorine or chlorine is spontaneously flammable [Mellor 4:267. 1946-47]. Magnesium Chloride G Magnesium Sulfate G Maleic Acid D Methanol L N-Methyl-2-Pyrrolidone L N,N Dimethylformamide L Nitric Acid E P-Dioxane L Paraformaldehyde L ... primary focus is concerning flammable liquids, flammable gases and Extremely/Acutely/Severally Toxic materials. Exposure to temperatures above 25°C/77°F during transport and storage will lead to minor losses in moisture content. Mylan Institutional LLC 1. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. It is a magnesium salt and a metal sulfate. Disappearance of the patellar reflex is a useful clinical sign to detect the onset of magnesium intoxication. Low magnesium levels don't cause symptoms in the short term. Explosion : It is not considered to be an explosion hazard. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. A serum magnesium level of 6 mg/100 mL is considered optimal for control of seizures. If Magnesium Sulfate is given for treatment of preterm labor, the woman should be informed that the efficacy and safety of such use have not been established and that use of Magnesium Sulfate beyond 5-7 days may cause fetal abnormalities. Rockford, IL 61103 U.S.A. Parenteral use in the presence of renal insufficiency may lead to magnesium intoxication. In magnesium: Principal compounds. Last updated on Oct 1, 2020. FIRST-AID MEASURES Eyes Rinse with plenty of water for at least 15 minutes and seek medical attention if necessary. Magnesium Sulfate, Created by Global Safety Management, Inc. -Tel: 1-813-435-5161 - www.gsmsds.com Methods and material for containment and cleaning up: If in a laboratory setting, follow Chemical Hygiene Plan procedures.Place into properly labeled containers for recovery or disposal. Available for Android and iOS devices. Monitoring serum magnesium levels and the patient’s clinical status is essential to avoid the consequences of overdosage in toxemia. Take this product by mouth as directed. The central and peripheral effects of magnesium poisoning are antagonized to some extent by intravenous administration of calcium. Hypermagnesemia in the newborn may require resuscitation and assisted ventilation via endotracheal intubation or intermittent positive pressure ventilation as well as IV calcium. The rate of I.V. Started to soak it in Epsom salts. If breathing is difficult, give oxygen. MATERIAL SAFETY DATA SHEET . Hypocalcemia with signs of tetany secondary to Magnesium Sulfate therapy for eclampsia has been reported. It is available in 4% concentration. Synthetically prepared magnesium sulfate is sold as Epsom salt, MgSO 4 ∙7H 2 O. In… These bone abnormalities include skeletal demineralization and osteopenia. Store at 20° to 25°C (68° to 77°F). Generic Name: Magnesium Sulfate heptahydrate Magnesium sulfate, anhydrous >99 7487-88-9 231-298-2 MgSO 4 120.37 g/mol 4. Larne, United Kingdom, clonazepam, lamotrigine, diazepam, topiramate, Lamictal, Valium, magnesium oxide, sotalol, acebutolol, Betapace. Clinical indications of a safe dosage regimen include the presence of the patellar reflex (knee jerk) and absence of respiratory depression (approximately 16 breaths or more/minute). Dosage Form: injection, solution. Continuous administration of Magnesium Sulfate is an unapproved treatment for preterm labor. Amphotericin B Find out more about how we use your information in our Privacy Policy and Cookie Policy. Fire Extinguishing Media : Use any means suitable for extinguishing surrounding fire. Higher temperatures lead to greater losses. It is a new type non-flammable material made of light weight materials. A total daily (24 hr) dose of 30 to 40 g Magnesium Sulfate should not be exceeded. If you have rectal bleeding or if you do not have a bowel movement after using magnesium sulfate as a laxative, stop using the medication and call your doctor at once. 5 years ago. Magnesium sulfate, MgSO 4, is a colourless crystalline substance formed by the reaction of magnesium hydroxide with sulfur dioxide and air.A hydrate form of magnesium sulfate called kieserite, MgSO 4 ∙H 2 O, occurs as a mineral deposit. Magnesium Sulfate in Water for Injection, can cause fetal abnormalities when administered beyond 5-7 days to pregnant women. 0 0. Synonyms : Magnesium / magnesium, borings / magnesium, metal / magnesium, ribbons / magnesium, scalpings / magnesium, sheet / magnesium, turnings BIG no : 10761 1.2. Water for Injection, USP is chemically designated H2O. Inhalation Move casualty to fresh air and keep at rest. Product is not flammable. Alcohol It is available in 4% concentration. Fiber cement panels are non-combustible building materials and offer amazing performance in fireproof, bending strength and impact resistance. Page: 1 of 3 . Subsequent intramuscular doses of 4 to 5 g of Magnesium Sulfate may be injected into alternate buttocks every four hours, depending on the continuing presence of the patellar reflex, adequate respiratory function, and absence of signs of magnesium toxicity. Drink plenty of liquids while you are taking magnesium sulfate. Magnesium Sulfate Heptahydrate is an odorless, colorless to white solid in crystalline form. For advice, contact the … As serum magnesium rises above 4 mEq/liter, the deep tendon reflexes are first decreased and then disappear as the serum level approaches 10 mEq/liter. Cool unopened containers with water. The safety and efficacy of such use have not been established. Magnesium Sulfate in Water for Injection is supplied as a clear, colorless solution in single-dose flexible plastic container as follows: * Partial fill container 50 mL volume in 100 mL container. Antagonized to some extent by intravenous administration of magnesium intoxication internet connection including! Clearly needed excreted in human milk material survey identified uses of the substance/mixture: Laboratory chemicals.! Lower serum levels of magnesium Sulfate taken orally should produce a bowel movement within 30 to. Recently from my son 's doctor is likely, use of impervious gloves is a found... Ph adjustment is immediate and lasts about 30 minutes is made from magnesium oxide, Sulfate... 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