PDF | On May 30, 2019, Monjur Ahmed published Peptic Ulcer Disease | Find, read and cite all the research you need on ResearchGate Clinical presentation and diagnosis of peptic ulcer. Pantoprazole sodium hydrate 718635-09-7-api, No public clipboards found for this slide. If you continue browsing the site, you agree to the use of cookies on this website. Peptic ulcer disease (PUD) is one of the commonest diseases seen throughout the world. The two major causes of PUD are Helicobacter pylori infection and NSAID usage. Peptic ulcer disease (PUD) occurs most commonly in duodenal bulb (duodenal ulcer, DU) and stomach (gastric ulcer, GU). AIMST University, Malaysia. Duodenal ulcer formation is related to hypersecretion of acid, possibly caused by overactive vagal stimulation. The prevalence of peptic ulcer and gastric ulcer was 9.4% and 4.7% in Taiwan, respectively [1,2]. An ulcer in the stomach is called a gastric ulcer, while one in the first part of the intestines is a duodenal ulcer. Ulcer :- An Ulcer is a discontinuity or break in a bodily membrane, or breach in the epithelium . The significant similarities in pathofhysiology and medical management make their discussion under one heading possible. Authors Varut Lohsiriwat 1 , Siriluck Prapasrivorakul, Darin Lohsiriwat. admission to intensive care) 5. Fig: Peptic ulcer disease Causes or Reasons for Peptic Ulcer Disease: The different causes for peptic ulcer are-Infection with Helicobacter pylori (H. Pylori), Use of painkillers called nonsteroidal anti-inflammatory drugs such as Ibuprofen, Aspirin, and Naproxen. Peptic ulcers: All four agents are equally effective in promoting healing of duodenal and gastric ulcers. 3. Carrie Jones; 2 Definition. Both types are referred to as peptic ulcers. Title: Stomach and Duodenum Peptic Ulcer - Pathology, clinical features, management Author: Administrator Last modified by: KFH Created Date: 9/2/2002 4:01:47 PM – A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 6d3260-NjAwO In the latter scenario, failure of medical management not uncommonly leads to surgical intervention. Peptic ulcer are among the most common known to man. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. • Duodenal ulcers are four times as common as gastric ulcers and occur mainly in the duodenal cap. Sina Hospital. Title: Peptic Ulcer Disease: 1 Peptic Ulcer Disease. The most common symptom of a peptic ulcer is stomach pain.Peptic ulcers include: 1. It may also occur in esophagus, pyloric channel, duodenal loop, jejunum, and Meckel’s diverticulum. Carrie Jones; 2 Definition. Cont’d. Precautions. Duodenal ulcers that occur on the inside of the upper portion of your small intestine (duodenum)The most common causes of peptic ulcers are infection with the b… Peptic ulcer disease (PUD) occurs most commonly in duodenal bulb (duodenal ulcer, DU) and stomach (gastric ulcer, GU). Now customize the name of a clipboard to store your clips. Barnard ; Dept. The initial management of a stable patient with dyspepsia differs from the management of an unstable patient with upper gastrointestinal (GI) hemorrhage. Post on 13-Nov-2014. (Uphold Graham, 2003) 3 Peptic Ulcers Gastric Dudodenal 4 PUD Demographics . Chronic peptic ulcer (stomach) is a mucosal defect which penetrates the muscularis mucosae and muscularis propria, produced by acid-pepsin aggression. Peptic ulcer disease (PUD) is a break in the inner lining of the stomach, the first part of the small intestine, or sometimes the lower esophagus. Some common types of peptic ulcer are: Duodenal ulcer: It occurs in duodenum just after the pylorus of the stomach. Treatment of peptic ulcers varies depending on the etiology and clinical presentation (see Guidelines). - Blood supply. The significant similarities in pathofhysiology and medical management make their discussion under one heading possible. The clinical presentation, diagnosis, treatment for gastric vs. duodenal ulcers are different. As for symptomatic presentation of peptic ulcer (Figure 1), stomach pain was the most frequently recorded symptom (88.4%) followed by hyperacidity (60.6%), underweight (57.4%), vomiting (40.6%), loss of appetite (39.4%) while vomiting of blood was found to be least frequent (7.7%). Your doctor may recommend tests to determine whether the bacterium H. pylori is present in your body. Perforated peptic ulcer: clinical presentation, surgical outcomes, and the accuracy of the Boey scoring system in predicting postoperative morbidity and mortality World J Surg. Document presentation format: On-screen Show (4:3) Company: org Other titles: Arial Wingdings Times New Roman Network 1_Network 2_Network 3_Network 4_Network 5_Network 6_Network 7_Network 8_Network 9_Network 10_Network 11_Network Peptic Ulcer Disease Definition Peptic Ulcers: Gastric & Dudodenal PUD Demographics Comparing Duodenal and Gastric Ulcers Duodenal Ulcers Gastric Ulcers … Generally peptic ulcer disease is encountered more frequently in males (M:F 3:1) 2and usually in the older population. The primary cause of peptic ulcer disease (approx. out of 18. Definition of peptic ulcer. Peptic ulcers most commonly occur in the duodenum and are more prevalent in patients between 40 – 60 years of age. We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. If you continue browsing the site, you agree to the use of cookies on this website. NSAIDs 3. corticosteroids 4. severe physiological stress/illness (e.g. Raika Jamali M.D. Peptic ulcers not associated with H pylori infection or the use of non-steroidal anti-inflammatory drugs are now also imposing substantial diagnostic and therapeutic challenges. Peptic Ulcer. PEPTIC ULCER 1. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Less common causes are severe physiological stress (e.g., severe illness, burns, or surgery) or hypersecretory states (e.g., Zollinger‐Ellison syndrome). He or she may look for H. pylori using a blood, stool or breath test. Natural history of peptic ulcer. Ulcer margins are regular, slightly elevated due to adjacent chronic gastritis. The breath test is the most accurate. Peptic ulcers not associated with H pylori infection or the use of non-steroidal anti-inflammatory drugs are now also imposing substantial diagnostic and therapeutic challenges. Most Popular; Study; Business; Design; Data & Analytics; Explore all categories; peptic ulcer disease ppt. [1] They newly began in around 53 million people in 2014 [4] About 10% of people develop a peptic ulcer at some point in their life [5]. Helicobacter pyloriinfection 2. Clipping is a handy way to collect important slides you want to go back to later. Free + Easy to edit + Professional + Lots backgrounds. Bleeding is also the major cause of mortality in patients older than 65 years [15]. 4. She looked for a PCP’s advice as she had a tarry stool in the early morning which she had never experienced before. -… Log in Upload File. Ulcers that form in the stomach are called gastric ulcers; in the duodenum, they are called duodenal ulcers. You can change your ad preferences anytime. for peptic ulcer in infected individuals ranges from 3% in the United States to 25% in Japan [14]. A peptic ulcer in the upper part of the small intestine (i.e. INTRODUCTION Peptic ulcer disease (PUD) is a common disorder that affects millions of individuals worldwide It is accounting for roughly 10% of medical costs for digestive diseases Higher prevalence in developing countries H. Pylori is sometimes associated with socioeconomic status and poor hygiene In the US Lifetime prevalence is ~10%. When it occurs in stomach its gastric ulcer. A peptic ulcer is a mucosal defect in the wall of the stomach or duodenum that penetrates the muscularis mucosa. Obtaining a medical history, especially for peptic ulcer disease, H pylori infection, ingestion of nonsteroidal anti-inflammatory drugs (NSAIDs), or smoking, is essential in making the correct diagnosis. Peptic Ulcer Disease (PUD) by FreeMedsite May 21, 2020 May 21, 2020. There are various risk factors for the development of peptic ulcer disease, but the most important ones are Helicobacter pylori infection and nonsteroidal anti-inflammatory drugs (NSAIDs). See our User Agreement and Privacy Policy. Epidemiology. The pain starts in the epigastrium but by the time of presentation in the emergency department, it is generalized and associated with diffuse peritonitis. However, there are many differences between children and adults, especially in the areas of clinical presentation, the prevalences of diffe … A circumscribed ulceration of the gastrointestinal mucosa occurring in areas exposed to acid and pepsin and most often caused by Helicobacter pylori infection. Risk factors include 2,4: 1. Often, they can tell you the exact timeof the perforation. PEPTIC ULCER DISEASE Hannah Vawda FY1 * * * * * * * * * * * * * * 1 calcium antagonists, nitrates, theophyllines, bisphosphonates, steroids and NSAIDs. Patient Case Presentation A 61-year-old American woman was referred to a Gastroenterology Clinic from primary care provider due to consistent discomfort and significant weight loss. - Blood supply. Eleven questions were scored on a linear scale and a symptom score was calculated. Some common types of peptic ulcer are: Duodenal ulcer: It occurs in duodenum just after the pylorus of the stomach. presentation of perforated peptic ulcer Patients with perforated PUD usually present with an acute onset of abdominal pain. Gastroenterologist and hepatologist. They resulted in 301,000 deaths in 2013 down from 327,000 deaths in 1990 [6]. Peptic Ulcer. Your digestive tract is coated with a mucous layer that normally protects against acid. Chronic use of NSAIDS (aspirin, ibuprofen, naproxen) weakens and thins the mucosal lining of the stomach and duodenum and greatly contributes to the formation of breaks in the protective lining. See our Privacy Policy and User Agreement for details. Looks like you’ve clipped this slide to already. If you continue browsing the site, you agree to the use of cookies on this website. Performing surgery as soon as possible, particularly in patients with delayed presentation or those older than 70 years. 2. ; The erosion of a circumscribed area may extend as deeply as the muscle layers or through the muscle to the peritoneum. Antiulcer pharmacology. Now customize the name of a clipboard to store your clips. A ‘Peptic Ulcer’ is any sort of ulcer that results from the action of stomach acid. Dr. J.H. Peptic ulcers occur when acid in the digestive tract eats away at the inner surface of the stomach or small intestine. Approximately 500,000 new cases are reported each year, with 5 million people affected in the United States alone. next. The ulcer is located on the jejunal side of the anastomosis, which is exposed to the chlorhydro-peptic secretion. But if the amount of acid is increased or the amount of mucus is decreased, you could develop an ulcer. Definition: Peptic ulcer is a hole or open sore in the lining of the stomach, duodenum (beginning of the small intestine) or oesophagus. In order to detect an ulcer, your doctor may first take a medical history and perform a physical exam. You then may need to undergo diagnostic tests, such as: 1. Drugs: NSAI, Aspirin, cortisone and cytotoxic drugs.. Cigarette smoking. Types. Marks IN, Johnston DA, Young GO: Acid secretory changes and early relapse following duodenal ulcer healing with sucralfate, ranitidine, antacids or omeprazole, in Halter F, Garner A (eds): Mechanisms of Peptic Ulcer Healing. 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